Bile acids extend longevity beyond calorie restriction

Bile acids extend longevity beyond calorie restriction

discovery of potential anti-aging treatment capable of extending both our healthy aging and perhaps our longevity resuscitated an old human dream. It also brought about inordinate interest in these studies. While calorie restriction (CR) is still the best known intervention to increase life span, anti-aging molecules could mimic this effect without reducing nutrient intake. Such compounds, like...

Calorie Restriction, Longevity and Cognitive Function

calorie restriction, longevity and cognitive function

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Telomerase Reverse Transcriptase Synergizes with Calorie Restriction to Increase Health Span and Extend Mouse Longevity

Caloric restriction (CR), a reduction of food intake while avoiding malnutrition, can delay the onset of cancer and age-related diseases in several species, including mice. In addition, depending of the genetic background, CR can also increase or decrease mouse longevity. This has highlighted the importance of identifying the molecular pathways that interplay with CR in modulating longevity. Si...

The Implications of Calorie Restriction on Longevity and Health Span

Calorie Restriction (CR) is a defined intervention tool currently being studied as an effort to achieve numerous health benefits and increase longevity. Currently, there is a large body of research that indicates a multitude of health benefits and positive associations; however, there is also a plethora of opposing research. Through investigation of epigenetics, the efficacy of calorie restrict...